Yes, that would be easy enough. In the simplest form, all you really need is an attribute in the User Profiles table that indicates whether or not that user is a paid subscriber. If they are, then give their content special attention.
Exactly what @Darren_Murphy said. You could do something like this:
In the user publications table, relate back to the user profile table and do a lookup of the user’s subscription status. If they’re an active member, then adjust the sorting of the publications so their content is first.